Kyle Lefkoff

Kyle Lefkoff, 66, is the Founder and General Partner of Boulder Ventures Ltd. In his forty years as a venture capitalist, Mr. Lefkoff has invested in 65 Colorado companies.

Mr. Lefkoff’s life science investments include Hauser Chemical Research (NASDAQ: HAUS); NeXstar Pharmaceuticals (sold to Gilead Sciences), Array BioPharma (sold to Pfizer), Dharmacon (sold to Fisher Scientific), Genomica (sold to Exelixis), miRagen Therapeutics (sold to Viridian Therapeutics), ArcherDX (sold to Invitae), Mineralys (NASDAQ: MYLS), and Ambrosia BioSciences.

Mr. Lefkoff founded Array BioPharma in May 1998 with Marv Caruthers and a group of Amgen scientists. Mr. Lefkoff was the Chairman of the Board of Array from its inception through August 2018, when its first drug, a targeted therapy for Melanoma, was approved by the FDA. In July 2019, Array was acquired by Pfizer for $11.8 Billion in cash, the largest acquisition of a venture-backed life sciences company in the history of Colorado.

Mr. Lefkoff was the lead venture capital investor in ArcherDX in its Series A round in 2018. He served as its Chairman and a Director until its sale to Invitae (NASDAQ: NVTA) in September 2020 for $2.4 Billion in cash and stock, the largest acquisition of a venture-backed life sciences tools company in the history of Colorado. He then represented the former shareholders of ArcherDX as their Shareholder’s Representative until the earnout was paid in July, 2021.

Mr. Lefkoff is the Chairman of Ambrosia BioSciences and a Founder of the company.

Mr. Lefkoff received his B.A. in Economics from Vassar College (summa cum laude) in 1981. In 1980, Mr. Lefkoff completed a Fellowship in Economic History at the London School of Economics. In 1985, he completed his MBA in Finance at the University of Chicago.

An experienced alpinist and mountain guide, Mr. Lefkoff is the Founding Chairman of the American Institute for Avalanche Research and Education (AIARE), the avalanche education standard among mountain guides and snow professionals in the USA. He is a Lifetime Member of the American Mountain Guides Association (AMGA) and was a member of the 1986 American Expedition to the North Face of K2.